About James Sweeney

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So far James Sweeney has created 326 blog entries.

Flotillin scaffold activity contributes to type VII secretion system assembly in Staphylococcus aureus

By |2017-11-23T17:36:35+00:00November 23rd, 2017|

Abstract Scaffold proteins are ubiquitous chaperones that promote efficient interactions between partners of multi-enzymatic protein complexes; although they are well studied in eukaryotes, their role in prokaryotic systems is poorly understood. Bacterial membranes have functional membrane microdomains (FMM), a structure homologous to eukaryotic lipid rafts. Similar to their eukaryotic counterparts, bacterial FMM harbor a scaffold [...]

Allergen immunotherapy for allergic asthma: A systematic review and meta-analysis

By |2017-11-23T17:29:41+00:00November 23rd, 2017|

Abstract Background To inform the development of the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines on Allergen Immunotherapy (AIT) for allergic asthma, we assessed the evidence on the effectiveness, cost-effectiveness and safety of AIT. Methods We performed a systematic review, which involved searching nine databases. Studies were screened against predefined eligibility criteria and [...]

Antibiotic-Resistant Gonorrhea: How Doctors Are Treating it in the Future

By |2017-11-23T17:25:45+00:00November 23rd, 2017|

Thanks to Jah Rule and the cast of Empire, we define a clapback as a savage comeback — exactly what gonorrhea, the STI your grandparents knew as “the clap”, is serving right now. A recent report from the World Health Organizationshows that antibiotic resistance is making gonorrhea — the second-most reported STI, infecting 820,000 people per year [...]

15 Tips To Cook Turkey Safely And Make America Gravy Again

By |2017-11-23T17:06:16+00:00November 23rd, 2017|

Two ways of making everyone sick this holiday season are to play the presidential election debates on a loop and food poisoning. Neither is good. Both may lead to vomiting and bowel problems. Food poisoning could send people to the hospital and in severe cases kill. Therefore, to avoid food poisoning this holiday season, follow these tips: 1. [...]

Rhinovirus Cs make use of less regulation…

By |2017-11-23T16:59:00+00:00November 23rd, 2017|

A new Australian study may help to explain why asthmatics have trouble suppressing the inflammation triggered by respiratory virus infections.[1] In particular, the inflammation due to members of one species of rhinovirus (RV), the RV-Cs, considered the worst of the “common cold” viruses for causing exacerbations or “asthma attacks”, in children with asthma. The study [...]

Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort

By |2017-11-23T16:51:13+00:00November 23rd, 2017|

Summary Background Increased concentrations of eosinophils in blood and sputum in chronic obstructive pulmonary disease (COPD) have been associated with increased frequency of exacerbations, reduced lung function, and corticosteroid responsiveness. We aimed to assess whether high eosinophil concentrations in either sputum or blood are associated with a severe COPD phenotype, including greater exacerbation frequency, and [...]

A Closer Look at Cognitive Function and Nutrition ‘Weight may accelerate aging of brain’ studies show

By |2017-11-23T01:42:29+00:00November 23rd, 2017|

In functional medicine, Alzheimer’s disease is often referred to as type 3 diabetes because studies show that glucose intolerance leads to an increased risk of developing Alzheimer’s disease and vascular dementia. Elevations in blood sugar levels may negatively affect memory and brain function, even in non-diabetic patients. A 2013 cross-sectional study that included 141 non-diabetic individuals found [...]

Identifying the hidden burden of allergic rhinitis (AR) in community pharmacy: a global phenomenon

By |2017-11-23T01:37:41+00:00November 23rd, 2017|

Abstract Background Patients with allergic rhinitis often trivialise their condition, self-manage inappropriately, and would benefit from health care intervention. The primary point of health care contact for these self-managing allergic rhinitis patients is the community pharmacy. With the majority of allergic rhinitis treatments being available for purchase over the counter, without health care professional contact, [...]

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