Nanomedicine for cancer immunotherapy: Spherical nucleic acids

By |2021-12-10T20:30:44+00:00December 10th, 2021|

A Northwestern University team has developed a method of optimising spherical nucleic acids, which could revolutionise nanomedicine for cancer immunotherapy in the future. Spherical nucleic acids are digitally designed nanostructures, which have DNA and RNA arranged on a nanoparticle’s surface. They have the ability to treat a wide range of diseases, but there is a need to optimise their [...]

Assessment of Sleep Disturbances and Exhaustion in Mothers of Children With Atopic Dermatitis

By |2021-12-10T20:30:44+00:00December 10th, 2021|

Key Points Question  Do mothers of children with atopic dermatitis experience sleep disturbances, and to what extent are these explained by child sleep disturbances? Findings  In this cohort study of 11 649 mother-child pairs, sleep disturbances were common among mothers of children with atopic dermatitis followed up from birth through age 11 years. Having a child with atopic [...]

Cells recall the way they were

By |2021-12-10T20:30:42+00:00December 10th, 2021|

Adult tissues retain — and can recover — a memory of their early development, which might be a game-changer for cancer and regenerative medicine A new study has found that adult cells keep a record of which genes were activated during their early development. Even more surprisingly, the memory is retrievable: Under certain lab conditions, [...]

Molecular Genetic Insights Into Varicella Zoster Virus (VZV), the vOka Vaccine Strain, and the Pathogenesis of Latency and Reactivation

By |2021-12-10T20:30:40+00:00December 10th, 2021|

Abstract Genetic tools for molecular typing of varicella zoster virus (VZV) have been used to understand the spread of virus, to differentiate wild-type and vaccine strains, and to understand the natural history of VZV infection in its cognate host.   Fisle CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)], from Wikimedia Commons Read more… The post Molecular Genetic Insights [...]

Molecular Evidence of Human Monkeypox Virus Infection, Sierra Leone

By |2021-12-10T20:30:40+00:00December 10th, 2021|

Monkeypox virus (MPXV), of the genus Orthopoxvirus, was identified in captive cynomolgus monkeys in Copenhagen in 1958 (1). The first documented case of human MPXV infection was reported in a patient from the Democratic Republic of the Congo in 1971 (2). Other outbreaks have occurred, including a large one in the United States in 2003, in [...]

Ebola cases pass 1,000 as DRC records 58 cases last week

By |2021-12-10T20:30:38+00:00December 10th, 2021|

Over the weekend and through today, the ministry of health of the Democratic Republic of the Congo (DRC) recorded 25 new Ebola cases from towns and cities across North Kivu and Ituri provinces, including two in Beni and one in Lubero. The rest of the cases originated in current hot spots, including Katwa and Butembo. [...]

Microparticle Responses to Aerobic Exercise and Meal Consumption in Healthy Men.

By |2021-12-10T20:30:35+00:00December 10th, 2021|

Abstract PURPOSE: Microparticles (MPs) are shed extracellular vesicles that express the pro-thrombotic tissue factor (TF). Aerobic exercise may reduce MP count and TF expression. This study investigated the impact of acute running or rest followed by standardised meal consumption on MP phenotypes and TF expression.   CC0 Creative Commons, Pixabay Read more… The post Microparticle [...]

Measles Cases and Outbreaks

By |2021-12-10T20:30:34+00:00December 10th, 2021|

Measles Cases in 2019 From January 1 to March 21, 2019, 314** individual cases of measles have been confirmed in 15 states. The states that have reported cases to CDC are Arizona, California, Colorado, Connecticut, Georgia, Illinois, Kentucky, Michigan, Missouri, New Hampshire, New Jersey, New York, Oregon, Texas, and Washington. *Cases as of December 29, [...]

New CRISPR-powered device detects genetic mutations in minutes

By |2021-12-10T20:30:21+00:00December 10th, 2021|

A team of engineers at the University of California, Berkeley and the Keck Graduate Institute (KGI) of The Claremont Colleges combined CRISPR with electronic transistors made from graphene to create a new hand-held device that can detect specific genetic mutations in a matter of minutes. ViktoriaAnselm [CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0)], from Wikimedia CommonsRead more… The [...]

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