Abstract The emergence of global antibiotic resistance necessitates the urgent need to develop new and effective antimicrobial agents. Combination of two antimicrobial agents can potentially improve antimicrobial potency and mitigate the development of resistance. Therefore, we have utilized metal molecular doping methodology whereby antimicrobial random peptides mixture (RPMs) are entrapped in a bactericidal copper metal [...]

Cardiovascular prevention measures should be considered in patients  with severe asthma exacerbation during hospitalization. An asthma exacerbation resulting in hospitalization greatly increases the risk for acute myocardial infarction (MI) and ischemic stroke in adults with poorly controlled asthma, according to study results published in the Journal of Allergy and Clinical Immunology: In Practice. CC0 Creative Commons [...]

Abstract Background As of February 25, 2019, 875 cases of Ebola virus disease (EVD) were reported in North Kivu and Ituri Provinces, Democratic Republic of Congo. Since the beginning of October 2018, the outbreak has largely shifted into regions in which active armed conflict has occurred, and in which EVD cases and their contacts have [...]

Abstract In the present study, we investigated the relation between cognitive performance and heart rate variability as a function of fitness level. We measured the effect of three cognitive tasks (the psychomotor vigilance task, a temporal orienting task, and a duration discrimination task) on the heart rate variability of two groups of participants: a high-fit [...]

Summary What is already known about this topic? Cryptosporidium is the leading cause of outbreaks of diarrhea linked to water and the third leading cause of diarrhea associated with animal contact in the United States. What is added by this report? During 2009–2017, 444 cryptosporidiosis outbreaks, resulting in 7,465 cases were reported by 40 states and [...]

ABSTRACT Despite antibiotics and sterile technique, postoperative infections remain a real and present danger to patients. Recent estimates suggest that 50% of the pathogens associated with postoperative infections have become resistant to the standard antibiotics used for prophylaxis. Risk factors identified in such cases include obesity and antibiotic exposure. To study the combined effect of [...]

Tuberculosis is treatable and curable, but newly published study findings showed that patients treated for — or cured of — TB still experience significantly increased mortality following treatment, with a pooled standardized mortality ratio, or SMO, nearly three times higher than the general population or matched controls, according to results from a systematic review and [...]

In an attempt to stimulate antibiotic development, the Centers for Medicare & Medicaid Services (CMS) is making changes to the way it reimburses hospitals for antibiotics and treatment of antimicrobial resistance (AMR). In a blog post in the journal Health Affairs on Friday, CMS administrator Seema Verma, MPH, outlined the changes, which include modifications to the way [...]

Abstract Background WHO identifies pregnant women to be at increased risk for severe outcomes from influenza virus infections and recommends that they be prioritized for influenza vaccination. The evidence supporting this, however, is inconsistent. Ecologic studies in particular suggest more severe outcomes from influenza infection during pregnancy than studies based on individual patient data. Individual [...]