Every additional day of antibiotic administration in the NICU results in lower anaerobe richness and butyrate producers, with more potential pathogens dominating the gut, study findings published in Clinical Infectious Diseases suggest.
According to Ashley M. Rooney, BSc, a PhD candidate at the University of Toronto, and colleagues, many infants in NICUs continue antimicrobial therapy without infection. Although discontinuation of unnecessary antibiotics is important for antimicrobial stewardship efforts, the researchers suggested that physicians may find it difficult.
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