CASE
Our patient is a 26-year-old female with cystic fibrosis (CF) (DF508/1898 + 1G>T), diagnosed at 2 weeks of age, who subsequently developed pancreatic insufficiency, impaired glucose tolerance, and osteopenia as a consequence of her CF. She was colonized with Staphylococcus aureus, with intermittent colonization of Pseudomonas aeruginosa since the age of 18 years. Her regular medication included pancreatic enzymes, nebulized hypertonic saline, salbutamol, and steroid inhalers. She could not tolerate flucloxacillin prophylaxis due to gastrointestinal side effects and found it difficult to accommodate regular antipseudomonal antibiotics.
Mikael Häggström [CC0], from Wikimedia Commons
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