Abstract

Background

Rhinovirus (RV) frequently causes asthma exacerbations among children and young adults who are allergic. The interaction between allergen and RV-induced symptoms and inflammation over time is unclear.

Objective

To compare the response to an experimental inoculation with RV-16 in allergic asthmatics and healthy controls, and evaluate the effects of administrating omalizumab before and during the infection.

Methods

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